Buy IGF-1 LR3 Peptide

IGF-1 LR3 is a synthetic variant of Insulin-Like Growth Factor 1, featuring an extended amino acid chain that significantly lowers its affinity for binding proteins, thus increasing its bioavailability. It functions by binding to IGF-1 receptors, activating intracellular signalling pathways like PI3K-AKT and MAPK, which facilitate cellular growth, proliferation, and differentiation. Compared to standard IGF-1, IGF-1 LR3 has a prolonged half-life and reduced binding to IGF-binding proteins, enabling more sustained interaction with target cells and amplifying its anabolic effects.

Sale!
IGF-1 LR3 Pre-Mixed Pen 1mg
£82.95 – £223.87 Select options This product has multiple variants. The options may be chosen on the product page
IGF-1 LR3 Peptide Vial
£20.85 – £89.35 Select options This product has multiple variants. The options may be chosen on the product page
Sale!
IGF-1 LR3 Nasal Spray
£88.37 – £171.74 Select options This product has multiple variants. The options may be chosen on the product page

IGF-1 LR3 Peptide Products

PharmaGrade.Store supplies high purity IGF-1 LR3 for research use, including:

- IGF-1 LR3 Peptide Vial – Lyophilized IGF-1 LR3 supplied in a sterile glass vial for intramuscular injection into the muscles. Please note you also require bacteriostatic water to reconstitute the peptide before use.
  Choose from 0.1mg or 1 mg IGF-1 LR3 vials.
- IGF-1 LR3 Nasal Spray – a ready to use peptide solution for painless administration via the nose. Choose from 15 ml or 30ml IGF-1 LR3 nasal sprays here.
- IGF-1 LR3 Pre-Mixed Peptide Pen – IGF-1 LR3 Peptide pen kits and cartridges come ready to use pre-mixed with bacteriostatic water. Peptide pens allow for precision dosing. Buy IGF-1 LR3 1mg Pre-Mixed Pen here.

IGF-1 LR3 for Research

Clinical studies have found that the IGF-1 LR3 peptide exerts its effects by binding to Insulin receptors (IGF-1R) on the surface of target cells. This receptor interaction triggers intracellular signalling cascades, primarily the PI3K-AKT and MAPK pathways [1].

These pathways play an important role in promoting cellular growth, proliferation, and differentiation. Through these mechanisms, IGF-1 LR3 stimulates protein synthesis, supports cell survival, and enhances repair processes in tissues, particularly muscle cells [2].

The peptide’s modified structure, featuring an extended chain and altered binding properties, reduces its interaction with IGF-binding proteins. This increases its bioavailability and allows for longer, more sustained activation of cellular receptors, amplifying its anabolic effects compared to standard IGF-1 [3].

Potential Benefits of IGF-1 LR3

In vitro testing has demonstrated that IGF-1 LR3 could have the following benefits and applications:

IGF-1 LR3 stimulates lean muscle growth – by stimulating protein synthesis and cell proliferation IGF-1 LR3 promotes muscle growth [2].
Improves muscle repair – IGF-1 LR3 enhances recovery through cellular differentiation improving tissue and cartilage repair, also reducing muscle breakdown [4].
Prolonged half-life – IGF-1 LR3 delivers more sustained anabolic effects compared to standard IGF-1 [3].
Potential treatment for muscle wasting diseases – IGF-1 LR3 could provide a therapeutic application in treating muscle-wasting conditions and age-related muscle loss [4].
Weight loss – Increased muscle mass caused by IGF-1 LR2 can elevate the body’s resting metabolic rate, allowing more calories to be burned even at rest, which could contribute to fat loss [5].

Scientific Research IGF-1 LR3

Scientific research on IGF-1 LR3 peptide highlights its significant role in muscle growth and repair. Laboratory studies show that it promotes protein synthesis and enhances tissue regeneration, making it promising for treating muscle-wasting diseases like sarcopenia or cachexia [4].

Scientific researchers have also focused on its activation of intracellular pathways, such as PI3K-AKT and MAPK, which are vital for cellular proliferation and differentiation [6]. Its prolonged half-life and increased bioavailability provide advantages over natural IGF-1, making it a key subject in fitness and therapeutic research.

Ongoing studies are exploring its potential in regenerative medicine and its broader applications in metabolic and age-related conditions.

IGF-1 LR3 Specifications:

View PharmaGrade Store IGF-1 LR3 HPLC Certificate here.

Sequence: MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA.

Molecular Formula: C400H625N111O115S9

Buy IGF-1 LR3 online from PharmaGrade.Store today!

Frequently Asked Questions about IGF-1 LR3

What sets IGF-1 LR3 apart from other versions of IGF-1?

IGF-1 LR3 distinguishes itself from other IGF-1 variants through specific molecular modifications and unique benefits. Studies have also found that it features an extended amino acid sequence with an additional 13 amino acids at the N-terminal, along with a substitution of arginine for glutamic acid at position 3. These changes enhance its stability and result in a significantly prolonged half-life of 20-30 hours, compared to the much shorter duration of other IGF-1 versions.

These modifications make IGF-1 LR3 exceptionally effective for systemic effects on muscle growth and recovery. Its extended presence in the bloodstream allows for continuous activation of cellular pathways responsible for protein synthesis and tissue repair. This is particularly advantageous in athletic and therapeutic contexts, where sustained support for muscle hypertrophy, healing, and overall recovery is required [7]. Unlike shorter-acting IGF-1 variants that may require frequent dosing or target localized applications, IGF-1 LR3 provides broader, long-lasting anabolic effects, making it a preferred choice for those focusing on comprehensive and enduring results.

Is IGF-1 LR3 legal?

The legality of IGF-1 LR3 can vary depending on the country and its specific regulations. In many places, IGF-1 LR3 is not approved for human consumption and is often sold for research purposes only. It’s important to check the specific laws and regulations in your country or region regarding the purchase, possession, and use of IGF-1 LR3. PharmaGrade.Store supplies IGF-1 LR3 for research purposes only.

Blogs:

The Healing Power of Peptide Therapy: A Guide to Tendonitis Treatment and Tissue Repair

We discuss the use of peptide therapy for treating tendonitis and enhancing tissue repair. The blog highlights how peptides, small chains of amino acids, can facilitate the body’s natural healing processes, offering a promising approach to conditions like tendonitis. The article emphasizes the potential of peptides like BPC-157, which has shown effectiveness in promoting tendon healing and reducing inflammation. It also explores other peptides such as Thymosin Beta 4 and growth factor peptides like MGF and IGF-1, which aid in tissue regeneration and repair.

Discover injury recovery peptides

Understanding MOTS-C Peptide for Metabolism Management

The article from PharmaGrade.store highlights how MOTS-c can improve glucose uptake and combat insulin resistance, potentially benefiting metabolic health and weight management. It also discusses the peptide’s ability to promote fat breakdown and support cellular resilience against oxidative stress. The blog suggests that ongoing research into MOTS-C and other peptides including IGF-1 LR3, HGH191AA and Thymosin Alpha-1 could lead to new therapeutic strategies for metabolic disorders, including type 2 diabetes and obesity.

Read the blog

Scientific Research:

[1] Baxter RC. Signaling Pathways of the Insulin-like Growth Factor Binding Proteins. Endocr Rev. 2023 Sep 15;44(5):753-778.

[2] Philippou A, Barton ER. Optimizing IGF-I for skeletal muscle therapeutics. Growth Horm IGF Res. 2014 Oct;24(5):157-63.

[3] Clemmons DR. Insulin-like growth factor binding proteins and their role in controlling IGF actions. Cytokine Growth Factor Rev. 1997 Mar;8(1):45-62.

[4] Song YH, Song JL, Delafontaine P, Godard MP. The therapeutic potential of IGF-I in skeletal muscle repair. Trends Endocrinol Metab. 2013 Jun;24(6):310-9.

[5] Thompson JL, Butterfield GE, Gylfadottir UK, Yesavage J, Marcus R, Hintz RL, Pearman A, Hoffman AR. Effects of human growth hormone, insulin-like growth factor I, and diet and exercise on body composition of obese postmenopausal women. J Clin Endocrinol Metab. 1998 May;83(5):1477-84.

[6] Tóthová Z, Šemeláková M, Solárová Z, Tomc J, Debeljak N, Solár P. The Role of PI3K/AKT and MAPK Signaling Pathways in Erythropoietin Signalization. Int J Mol Sci. 2021 Jul 19;22(14):7682.

[7] Bailes J, Soloviev M. Insulin-Like Growth Factor-1 (IGF-1) and Its Monitoring in Medical Diagnostic and in Sports. Biomolecules. 2021 Feb 4;11(2):217.

Buy IGF-1 LR3 from PharmaGrade.Store Online

ALL PRODUCT INFORMATION AND ARTICLES ON THIS SITE ARE FOR EDUCATIONAL PURPOSES ONLY

DISCLAIMER: All products sold by PharmaGrade.Store are for research and laboratory use only. These products are not designed for use or consumption by humans or animals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such. By purchasing from our Website the buyer accepts and acknowledges the risks involved with handling of these products. All articles and product information provided on this Website are for informational and educational purposes only. Handling and use of these products should be restricted to suitably qualified professionals